Study Guide BIOL 3090 chapters 15 and 17

Chapter 15 - an important chapter

15.1  Diffusion of small molecules Figure 15-1

15.2  Types of membrane transporters

uniporter, symporter, antiporter Figure 15-3

15.3 facilitated transport

glucose transport

Figures 15-4, 15-5, 15-7

15.4 ion movement

ion concentrations Table 15-1

membrane potential Figure 15-8, 15-9

15.5  Active transport

ATP-powered transporters Figure 15-10*, Table 15-2

Ca²⁺ ATPase Figures 15-11, 15-12

Na⁺ - K⁺ ATPase Figure 15-13

ABC transporters Figure 15-15 cystic fibrosis page 597

15.6  Cotransport

Na⁺ - glucose cotransporter Figure 15-18, 15-19

Band three of erythrocytes (AE1 protein) Figures 15-20, 15-21

15.7  epithelial transport

tight junction, glucose uptake in the intestine (Figure 15-25, 15-28)

15.8 Osmosis

transport of water, aquaporin Figures 15-32, 15-33

Questions 4, 6, 7, 11-13

Where are proteins made? (Figure 17-1, Table 17-1)

17.1 Mitochondrial and chloroplastic protein targeting (Figure 17-2)

Uptake by mitochondria - know the general pathway Figures 17-2, 17-3, 17-5

Uptake by chloroplasts - know the general pathway Figure 17.8

17.2 peroxisomal proteins  

Peroxisome biogenesis, SKL target sequence Figure 17.10

17.3  Secretory pathway overview Figure 17-12, 17-13*

five types of secretory mutants - Figure 17-14*

17.4  Translocation of proteins across the ER membrane

SRP and SRP receptors Figures 17-15, 17-16, 17-17

TRAM Figure 17-18

17.5 Membrane proteins

Stop transfer sequence Figures 17-21, 17-22, 17-23*, 17-24*

17.6  Post-translational modification

disulfide bonds, protein folding  Figure 17-26

KDEL receptor Figure 17-29

17.7 protein glycosylation

N-linked and O-linked sugars

ABO blood type (Table 17-2, Figure 17-34

Figures 17-35, 17-36

Lysosome targeting figures 17-39, 17-40

17.8 Protein processing

Proteolytic cleavage Figure 17-41

17.9 Receptor-mediated endocytosis, sorting

Low-density lipoprotein (LDL) particle and LDL-receptor Figures 17-45, 17-46

Transcytosis uptake of antibodies by babies Figure 17-49

17-10 Molecular traffic

Mechanisms of vesicle trafficking Figure 17-50

coated vesicles, clathrin, and non-clathrin coated vesicles Figures 17-51, 17-52, 17-53, 17-54, 17-58

V-SNARE and Rab proteins Figure 17-59 

Questions 1-14