Simon H. Chang

Professor Emeritus
Ph.D., Oklahoma State University, 1965
Molecular structure and function of metabolic enzymes; regulation of tissue-specific expression; mechanisms of mutagenesis.

schang@lsu.edu

Studies on the structural basis of allosteric regulation in phosphofructokinase.

Selected Publications

Auzat, I., Bynes, M., Grrel, J-R. and Chang, S.H. 1995. The role of residue 161 in the allosteric transitions of two bacterial phosphofructokinase. Biochemistry 34, 7062-7068.

Zbu, X., Byrnes, M., Nelson, J.W. and Chang, S.H. 1995. The role of glycine-212 in the allosteric behavior of phosphofructokinase form B. stearothermophilus. Biochemistry 34, 2560-2565.

Li, J., Zhu, X., Byrnes, M. Nelson, J.W. and Chang, S.H. (1993) Site-directed mutagenesis of rabbit muscle phosphofructokinase cDNA: Mutations at Glutamine 200 affect the allosteric properties of the enzyme. J. Biol. Chem. 268, 24599-24606.

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