Biochemistry 


·        Degree Programs

·        Program Overview

·        Facilities

·        Contact

·        Admission

·        Financial Assistance

·        Graduate Faculty

DEGREE PROGRAMS

The Department of Biological Sciences offers research-oriented M.S. and Ph.D. degrees in Biochemistry. Qualified students usually enter the Ph.D. program without first earning a M.S. degree. Requirements for the Ph.D. include appropriate coursework designed to provide broad but intensive training in biochemistry, experience in presentation of seminars and successful completion of qualifying and general examinations. The Ph.D. also requires formulation and execution of original research, as demonstrated by production of research publications and a dissertation. The M.S. requires a thesis and a minimum of 30 semester hours of graduate work, 24 hours of which must be in coursework. At least one-half of the minimum required credit in the M.S. program must be in courses at or above the 7000 level.

PROGRAM OVERVIEW

Graduate programs offered by the Department of Biological Sciences in the area of biochemistry prepare students for professional careers in biochemical research and teaching. Research interests within the department encompass a broad range, including cell and molecular biology, virology, plant biochemistry, enzymology, and protein, DNA, and carbohydrate molecular biophysics.

FACILITIES

The Department of Biological Sciences is primarily housed in the Life Sciences Building, that recently was expanded by a major addition, and Choppin Hall, which also houses the Department of Chemistry. The Laboratories are designed for conducting modern research in diverse fields including biochemistry and molecular biology; cell, organismal and integrative physiology; ecology, systematics, and evolutionary biology; plant biology; microbiology and molecular genetics. Several large facilities with technical help and state-of-art instrumentation facilitate research at LSU and include laboratories for Functional Genomics (DNA sequencers, real time PCR, Scan Array and Microarray equipment), NMR analysis and mass spectrometry (Kratos high-resolution, Finnigen tandem, and Bio-Ion Plasma Desorption time-of-flight mass spectrometers), and confocal, light and electron microscopy (in the Socolofsky Microscopy Center). Common instruments and facilities include tissue culture facilities, media preparation facilities, darkrooms, walk-in cold rooms, plant-growth chambers, animal facilities and aquatic facilities.  Research support comes from the Louisiana State University Gene Probes and Expression Systems Laboratory, the Protein Facility , and the Macromolecular Computing Analysis Facility. The personnel of the Department of Experimental Statistics are available to help design experiments and analyze data.

The recent addition of a Beowulf cluster provides a computer system that will run at 2.1 TeraFlops, or 2.1 trillion floating-point operations per second. This would rank it among the six or seven fastest computers in the world, and second among academic institutions worldwide. An initiative in Biological Computing is a part of this new investment by the State of Louisiana. 

Students and faculty also have access to the research collections of the Museum of Natural Science (with more than 350,000 specimens) and the LSU Herbarium (home to many specimens of land plants, lichens, and fungi) as well as many of the research facilities of the Louisiana Agricultural Experiment Station and Louisiana Sea Grant. Louisiana Universities Marine Consortium (LUMCON) provides support for marine/estuarine research and maintains two research vessels for offshore research and numerous smaller boats for inshore sampling. Field research by department members is conducted in numerous tropical, subtropical, temperate and high-latitude locations. Biological Sciences faculty collaborate with scientists throughout LSU including the Departments of Animal Science, Chemistry, Plant Pathology and Crop Physiology, Oceanography and Coastal Science, the Pennington Biomedical Research Center, the Audubon Sugar Institute, the Institute for Environmental Studies, Civil and Environmental and Chemical Engineering, and the School of Veterinary Medicine, as well as universities and research centers throughout the nation and world.

CONTACT

For more information, please contact the Office of Graduate Studies, Department of Biological Sciences. We may be reached directly at (225)578-1556 or gradoff@lsu.edu , or by mail at: Graduate Studies, Department of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803.
 

ADMISSION

Applications for graduate study are accepted at any time, but they are evaluated only after all supporting documents and credentials have been received. Applications should be initiated at least 7-9 months prior to anticipated entry. For Fall admission, we recommend applications be submitted by the end of the preceding year. By the time of admission, applicants should have earned a minimum of a baccalaureate degree with training in the areas our own undergraduates receive.  These include courses in general and advanced biology (including genetics and biochemistry), inorganic and organic chemistry, calculus, introductory physics, and physical chemistry.  Qualified students lacking one or two of these areas may remedy the deficiencies after admission. Applicants must score at least 1100 on the GRE (verbal plus quantitative scores, analytical is not included) and 550 (paper test) or 213 (computer test) on the TOEFL (for international students) in order to be considered for admission. An overall GPA of at least 3.00 ("A" = 4.0) is required.

Application is completed by following the simple steps below:

1. Submit to the Graduate School (114 David Boyd Hall, LSU Baton Rouge, LA 70805):

2.  Have the following sent to the Department of Biological Sciences:

FINANCIAL ASSISTANCE

Teaching Assistantships and Board of Regents’ Fellowships are available from the Department. Research Assistantships are available from grant support to individual faculty members. All awards are competitive. Assistantships provide annual stipends ranging from $13,250 for M.S. candidates, and $15,250 base pay for Ph.D. students; the latter may be supplemented ($3,000) or enhanced ($5,000) to provide a higher overall stipend.

Outstanding Ph.D. applicants may be awarded Board of Regents’ Fellowships. These research fellowships may be renewed for up to four years, with renewal subject to annual review. Fellowships carry no teaching responsibilities beyond the one semester departmental requirement, include complete tuition waiver and an $20,000 annual stipend.

To be considered for support for fall matriculation, applications must be completed by the end of the year preceding  the year of admission.

 

GRADUATE FACULTY

(Most names are linked to faculty web pages which contain a research description and a list of recent publications)

Fareed Aboul-ela NMR, RNA Structure, Small-molecule RNA interactions

Sue G. Bartlett    Chloroplast protein biogenesis, synthesis, and transport

John R. Battista     Molecular biology; mechanisms of mutagenesis in Deinococcus radiodurans and Saccharomyces cerevisiae

Mark A. Batzer    Human genomics, evolution

Terry M. Bricker    Structural and functional properties of Photosystem II

Richard C. Bruch     Signal transduction

Simon H. Chang    Molecular biology and recombinant DNA technology; investigations of regulation of PFK

Stephania Cormier    Immunopathology, lung cell and molecular biology, regulation of gene and protein explosion, neonatal immunity

Patrick J. DiMario    Interactions of nucleolar proteins involved in RNA and ribosome processing and assembly

Huangen Ding     Regulatory function and metabolism of iron sulfur proteins

William T. Doerrler     Membrane biogenesis in E. coli

David Donze      Chromatin structure and gene expression

Anne Grove     Protein-nucleic acid interactions; DNA bendability; RNA polymerase III from yeast

Hollie-Hale Donze     Infection and Immunity

Brian J. Hales    Characterization of metalloproteins and nitrogenase by ESR and magnetic circular dichroism

Steven Hand    Bioenergetics, molecular physiology, environmental control of gene expression, comparative biochemistry

Craig M. Hart     Chromosome organization, chromatin structure and gene expression

Roger A. Laine    Carbohydrate, glycolipid, and glycoprotein structural analysis by mass spectrometry

John C. Larkin    Molecular genetics, plant development biology

Yong-Hwan Lee    Structure/function studies of the metabolic regulator proteins and their regulatory mechanisms

Vince J. LiCata    Protein structure & function, energetics

Thomas S. Moore    Regulation of membrane lipid synthesis in plant organs and cell cultures

James V. Moroney    Role of membrane transport and carbon dioxidefixation in photosynthesis and bioenergetics

Marcia Newcomer     Protein crystallography

Gregg S. Pettis     Molecular Biology; mechanism of conjugation in the gram positive bacteria Streptomyces and Mycobacteria

Kirsten Prüfer    Cell Biology of nuclear receptors, trafficking nuclear import and export, molecular endocrinology, biochemistry, molecular biology

William A. Pryor    Chemistry, biochemistry, and toxicology of free radical reactions

Jacqueline M. Stephens     Cell biology

Grover L. Waldrop    Mechanistic enzymology and structure/function relationships in proteins

Tin-Wein Yu    Functional genetics of microbial metabolites and structural diversity of natural products

G. Wayne Zhou    Structure and Function of protein tyrosine phosphatases; Structure and Function of the phox (PX) domain-containing proteins. Identifying potential biomarkers for cancer diagnosis by using antibody microarray staining

Adjunct Faculty in BMB

K. Gus Kousoulas     Molecular biology of herpes viruses by general and site-specific mutagenesis

Randall Mynatt     Obesity, transgenics

Kathy O' Reilly

Steven R. Smith     Adipocyte biology, energy expenditure, metabolism

Jianping Ye        Antioxidant and Gene Regulation Lab; insulin and leptin signaling mechanisms

 

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